Genes & Medications

Comprehensive gene analysis means more effective personalized care for patients

The G.A.P Test analyzes 20+ genes known to affect the metabolism of more than 300 medications. Specifically, our test covers the most studied class of enzymes, cytochrome p450, which are essential for the metabolism of many medications including Plavix and Coumadin, two of the medications for which pharmacogenetic testing is commonly recommended. The following enzymes covered by The G.A.P Test have been scientifically proven to affect a patient’s response to a variety of frequently prescribed drug classes, including beta-blockers and antidepressants.

Enzymes analyzed include:


Drugs covered:

  • aripiprazole (Abilify)
  • citalopram (Celexa)
  • desipramine (Norpramin)
  • doxepin (Adapin, Silenor, Zonalon)
  • escitalopram (Lexapro)
  • imipramine (Tofranil)
  • nortriptyline (Aventyl Hydrochloride, Pamelor)
  • sertraline (Zoloft)
  • trimipramine (Surmontil)
  • venlafaxine (Effexor)
  • And More

Birth Control

  • hormonal contraceptives (Ortho Tri-Cyclen, Seasonique, Yasmin)


  • clopidogrel (Plavix)
  • flecainide (Tambocor)
  • metoprolol (Lopressor, Toprol-XL, Metoprolo Succinate ER)
  • propafenone (propafenone systemic)
  • warfarin (Coumadin, Jantoven)
  • And More


  • simvastatin (Zocor, Vytorin, Simcor)
  • And More


  • esomeprazole (Nexium, Vimovo)
  • lansoprazole (Prevacid)
  • omeprazole (Prilosec, Zegerid, Omesec)
  • pantoprazole (Protonix)
  • And More


  • mercaptopurine  (Purinethol, Purixan)
  • thioguanine (Tabloid)
  • And More


  • phenytoin (Dilantin, Phenytek)
  • And More


  • capecitabine (Xeloda)
  • fluorouracil (Adrucil, Carac, Efudex)
  • irinotecan (Camptosar)
  • tamoxifen (Nolvadex, Tamofen, Tamoxen)
  • tegafur (Uftoral, Tegafur)
  • And More

Pain Management

  • codeine (Robitussin-AC, Tylenol with Codeine,Cotabflu)
  • oxycodone (Percocet, OxyContin, Roxicodone)
  • tramadol (Ultram, ConZip, Ultracet)
  • And More


  • amitriptyline (Elavil, Endep, Vanatrip)
  • atomoxetine (Strattera)
  • haloperidol (Haldol)
  • risperidone (Risperdal)
  • And More


  • azathioprine (Azasan, Imuran)
  • And More